The sound bites are familiar, according to news articles from 1918 and 1919. This review will describe actual short-term and long-term outcomes of patients with severe ARDS treated with ECMO and summarize the characteristics and performance of published survival prediction models. They described slightly impaired lung function with a mildly obstructive pattern (forced expired volume at 1 second < 80%). "1918 was particularly hard on young adults, those in the childbearing years, [while] COVID-19 is particularly hard on older adults," Crimmins says. Targeting populations that can most benefit from this therapy is now of major importance. Aubron C, Cheng AC, Pilcher D, Leong T, Magrin G, Cooper DJ, Scheinkestel C, Pellegrino V. Infections acquired by adults who receive extracorporeal membrane oxygenation: risk factors and outcome. Camboni D, Philipp A, Lubnow M, Bein T, Haneya A, Diez C, Schmid C, Müller T. Support time-dependent outcome analysis for veno-venous extracorporeal membrane oxygenation. 2008;79:54–60. The . infection with 10 TCID 50 of influenza virus A/FM/1/47 (H1N1). 2014;189:1374–82. Fifty-seven per cent of patients were alive at hospital discharge after a median of 170 hours on ECMO. 1). Moreover, ECMO-treated survivors exhibit significant rates of long-term neuro-psychological and/or physical impairment [7]. Looking beyond the scientific unknowns or misinformation in popular media, one thing is clear, according to Crimmins and Finch: Preventing as much further infection as possible will be our best bet for staving off the worst long-term outcomes. Luyt C-E, Combes A, Becquemin M-H, Beigelman-Aubry C, Hatem S, Brun A-L, Zraik N, Carrat F, Grenier PA, Richard J-CM, Mercat A, Brochard L, Brun-Buisson C, Chastre J, REVA Study Group. Lindén VB, Lidegran MK, Frisén G, Dahlgren P, Frenckner BP, Larsen F. ECMO in ARDS: a long-term follow-up study regarding pulmonary morphology and function and health-related quality of life. Click here to sign in with My 20-year old son had H1N1 back in 2009. Infections occurring during extracorporeal membrane oxygenation use in adult patients. 2013;39:275–81. Crit Care Resusc. Roch A, Hraiech S, Masson E, Grisoli D, Forel J-M, Boucekine M, Morera P, Guervilly C, Adda M, Dizier S, Toesca R, Collart F, Papazian L. Outcome of acute respiratory distress syndrome patients treated with extracorporeal membrane oxygenation and brought to a referral center. Am J Respir Crit Care Med. According to a recent study published in JAMA, even asymptomatic people who have tested positive for SARS-CoV-2 infection have been found to have signs of tissue damage, including myocarditis, or inflammation of the heart. Myhren H, Ekeberg Ø, Stokland O. Health-related quality of life and return to work after critical illness in general intensive care unit patients: a 1-year follow-up study. However, given the fact that most of the predictive variables described have been recorded during the immediate pre-ECMO period, it is likely that the same factors which predict survival in populations who are on ECMO may also be helpful to select patients for consideration of ECMO.
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